GRANTED INVENTION PATENT

Technology Title: Process for the Preparation of Fatty N-Acylamino Hydrazides and Their Use in the Synthesis of Metallic Nanoparticles

Inventors:

Marcelo Gonçalves Montes D'Oca (Lattes CV)
Marcos Alexandre Gelesky (Lattes CV)
Renata Fontes Ongaratto (Lattes CV)

Academic Unit: School of Chemistry and Food – EQA

Overview:
The present invention describes the synthesis of novel fatty N-acylamino hydrazides derived from fatty acids and their application in the synthesis of metallic nanoparticles. The newly proposed derivatives—designated as fatty N-acylamino hydrazides—are obtained by incorporating fatty chains derived from renewable sources, such as vegetable oils and fatty acids.

This invention enables the synthesis of new fatty N-acylamino hydrazide compounds that serve dual roles in metallic nanoparticle synthesis: as reducing agents (due to the hydrazide functional group) and as stabilizing agents (due to both their polar portion, which provides electrostatic stabilization, and their high lipophilicity). The lipophilic character arises from the incorporation of alkyl chains containing 4 to 26 carbon atoms, which may be saturated, unsaturated, linear, branched, or substituted with groups containing N, O, or S.

These compounds are synthesized via a simple procedure and in good yields. Consequently, the novel fatty N-acylamino hydrazides allow for a streamlined, rapid, and cleaner synthetic methodology for producing metallic nanoparticles—since they function simultaneously as both reducing and stabilizing agents, eliminating the need for additional reagents to perform these roles.

Patent Status: Granted. PATENT LETTER NO. BR 10 2016 023072 1, issued on March 31, 2023.

Abstract: Available at this link.